摘要
目前乳酸菌的防治糖尿病功效已得到广泛认可。本文综述国内外关于乳酸菌应用于临床糖尿病治疗的研究进展,对乳酸菌可能的降血糖作用机理及物质基础进行了分析总结,并对目前存在的安全性问题和今后研究方向进行探讨,希望为糖尿病防治提供新的思路,为开发新型降糖药物提供一定的理论依据。
Hypoglycemic activities of many kinds of lactic acid bacteria have been proved.The article summarized current clinical applications and the research progress on hypoglycemic activity of lactic acid bacteria,and their hypoglycemic mechanism and bioactive compounds were analyzed.The safety and the future direction of research in this field were also discussed.The results of this study provided reference for exploiting new hypoglycemic drug from lactic acid bacteria for the treatment of diabetes.
出处
《天然产物研究与开发》
CAS
CSCD
北大核心
2012年第9期1323-1329,共7页
Natural Product Research and Development
基金
科技部973计划(乳品安全控制和新型乳品加工关键技术研究
2010CB735705)
上海乳业生物工程技术研究中心(09DZ2251400)
关键词
乳酸菌
糖尿病
降血糖
作用机制
lactic acid bacteria
diabetes mellitus
hypoglycemic activity
mechanism