自拟健脾化湿汤治疗非酒精性脂肪肝53例疗效观察

Curative Effect on the Treatment of 53 Cases of Non-alcoholic Fatty Liver with the Self-prescribed Jianpihuashitang Decoction

目的:观察自拟健脾化湿汤治疗脾虚湿蕴证非酒精性脂肪肝的疗效。方法:对106例脾虚湿蕴证非酒精性脂肪肝患者按就诊顺序1:1等分为自拟健脾化湿汤方治疗组、对照组两组,每组病例53例。两组患者在强调戒酒,控制饮食,加强运动的基础上,治疗组采用自拟中药健脾化湿汤治疗,对照组选用多烯磷脂酰胆碱胶囊治疗。用药疗程为3个月,疗程结束后统计疗效。结果:两组患者症状疗效比较,治疗组明显优于对照组(P<0.01);两组患者治疗前后肝功能变化比较,治疗组优于对照组(P<0.05);两组患者治疗前后血脂变化比较,治疗组优于对照组(P<0.05);两组治疗前后CT检查结果比较,治疗组优于对照组(P<0.05)。结论:自拟健脾化湿汤治疗脾虚湿蕴证非酒精性脂肪肝疗效显著。

Objective： To observe the efficacy of Self-prescribed Jianpihuashitang Decoction on Spleen Deficiency, and Damp Retention of Non-alcoholic Fatty Liver. Methods： 106 cases of spleen deficiency with damp retention of non-alcoholic fatty liver were alloca ted equally to group treated with self-prescribed Jianpihuashitang Decoction, and the control group, each group had 53 cases. Two groups were all on the basis of abstinence from alcohol, adherence to a diet and increase of physical activity. Treatment group was given self-prescribed Jianpihuashi Decoction, the control group was given polyene phosphatdyl choline capsules. After 3 months of treatment. Results： The symptoms and efficacy of two groups of patients were compared, the effect of the treatment group significantly surpasses the control group （P〈0.01）. The liver function before and after treatment were compared, the effect of the treatment group significantly surpasses the control group （P〈0.05）. The lipid changes before and after treatment were compared, the effect of the treatment group signific- antly surpasses the control group（P〈0.05）. The CT findings before and after treatment were compared, the effect of the treatment group significantly surpasses the control group （P〈0.05）. Conclusion： Self-prescribed Jianpihuashi Decoction shows significant effects on spleen deficiency with damp retention of non-alcoholic fatty liver treatment.