阴道镜活检联合LEEP术诊治宫颈病变的疗效分析

Analysis of the Effect of Diagnosis and Treatment of Cervical Lesion by Colposcopy and Biopsy Combined with LEEP

目的:探讨阴道镜活检联合宫颈环形电切术(LEEP术)诊治宫颈病变的疗效。方法:对354例宫颈病变患者在阴道镜下多点活检后行LEEP术治疗,并做病理组织学诊断,观察患者的手术时间、术中出血量及治疗效果,比较两种方法取材的病理组织学诊断结果。结果:LEEP术的平均手术时间长约6.76.7±3.5 min,术中出血量<20 mL。2个月后患者复查,成功率为93.8%(332/354例),经二次手术全部治愈,并发症少。从病理组织学诊断结果来看,与LEEP术相比,阴道镜下活检的炎症检出率高,宫颈上皮内瘤变的检出率低,但差异均无显著统计学意义(P>0.05)。结论:根据阴道镜活检结果,针对性使用LEEP术,密切随访,是诊治宫颈病变的有效方法。

Objective： To investigate the effect of diagnosis and treatment of cervical lesion by colposcopy and biopsy combined with LEEP. Methods： 354 cases with cervical lesions were firstly treated with biopsy via colposcopy and then operated with LEEP. All acquired tissue were sent for pathological diagnosis. The intraoperative, postoperative conditions and effects were observed. Results： The average operative time of LEEP was 6.7 min with less blood loss. 2 months after operation, the surgical success rate was 93.8%, which reached 100% after secondary surgery with less complications. Higher detection rate of inflammatory and lower detection rate of CIN I, CIN II, CINIII via biopsy under colposcopy was observed than LEEP. But there was no significant difference （P〉0.05）. Conclusions： Based on colposcopy and biopsy results, targeted use of LEEP was effective mean to diagnose and treat cervical lesions.