白术生地升麻汤治疗小儿功能性便秘(脾虚型)50例

50 cases of spleen deficiency of pediatric functional constipation treated with Atractylodes macrocephala,Rehmannia glutinosa and Rhizoma Cimicifugae Decoction

目的:观察白术生地升麻汤治疗小儿功能性便秘(脾虚型)的临床疗效。方法:95例功能性便秘(脾虚型)患儿,按门诊挂号单双号随机分为2组,治疗组50例口服白术生地升麻汤,对照组45例口服麻仁滋脾丸,治疗15 d后统计疗效,于停药后3月随访患儿症状改善情况。结果:治疗组总有效率96%,明显高于对照组的82%,差异有统计意义(P<0.05)。治疗组随访36例中出现大便干结6例,厌食8例,腹胀、腹痛12例;对照组随访30例中出现大便干结26例,厌食24例,腹胀、腹痛28例。2组比较,差异有统计意义(P<0.05或P<0.01)。结论:白术生地升麻汤治疗小儿功能性便秘(脾虚型)疗效显著。

Objective： To observe the clinical curative effect of Atractylodes macrocephala, Rehmannia gluti- nosa and Rhizoma Cimicifugae Decoction in the treatment of pediatric functional constipation （of spleen deficiency type）. Methods： 95 patients with functional constipation, according to their odd or even registration number, were randomly divided into 2 groups. 50 cases in treatment group, orally taking Atractylodes macrocephala, Rehmannia glutinosa and Rhizoma Cimicifugae Decoction. 45 cases in the control group orally taking Marenzipi Pills. 15 days after, the data was collected. 3 months after, the follow-ups were made to observe the symptomatic improvement. Results： The total effective rate in the treatment group was 96% , significantly higher than that in control group, which was 82% , the difference was statistically significant （P〈0.05）. 36 cases in the treatment group were fol- lowed up with 6 cases of dry stool, 8 cases of anorexia, 12 cases of abdominal distention and pain; 30 cases in the control group were followed up, 26 cases of dry stool g24 cases of anorexia, 28 cases abdominal distention and pain. The difference has statistical significance（P〈0.05 or P〈0.01）. Conclusion： Atractylodes maeroeephala, Reh- mannia glutinosa and Rhizoma Cimicifugae Decoction can get obvious effect in treating pediatric functional constipa- tion （ effect of spleen deficiency type）.