肠内营养与肠外营养支持治疗重症急性胰腺炎的临床疗效对比观察

Comparative efficacy of enteral nutrition and parenteral nutrition for the severe acute pancreatitis

目的观察比较肠内营养(EN)与肠外营养(PN)分别用于重症急性胰腺炎(SAP)的临床疗效。方法将31例SAP患者随机分为试验组16例和对照组15例。试验组采用EN方式,对照组给予PN方式。观察2组在血清学指标、急性生理功能和慢性健康状况评分系统Ⅱ(APACHEⅡ)评分多层螺旋CT(Balthazar CT)评分及并发症发生情况。结果试验组血淀粉酶、血常规及C-反应蛋白(CRP)恢复时间均短于对照组,APACHEⅡ评分和Balthazar CT评分均低于对照组,并发症发生率均低于对照组,差异均有统计学意义(P<0.05)。结论 SAP患者早期进行EN较PN更可靠、有效,可作为SAP营养支持治疗的首选。

Objective To compare the clinical effect of enteral nutrition （EN） and parenteral nutrition （PN） for severe acute pancreatitis （SAP）. Methods 31 cases patients with SAP were divided into experimental group （ 16 cases） and control group（ 15 cases）. Experimental group was given EN, control group was given PN. Observed the serum level, APACHE II score Balthazar CT score and complications of two groups. Results The time to normalization of the serum amylase, blood routine and C-reactive protein in experimental group were less than those in control group;The APACHE II score and Balthazar CT score in experimental group were lower than those in control group, the complication rate of experimental group was lower than that of control group, the difference were statistically significant （P 〈 0.05）. Conclusion It is more reliable and effective for SAP to administrate EN early, EN may be the first choice for the SAP.