AIDS相关脑内淋巴瘤的影像诊断及鉴别

Imaging features and differential diagnosis of primary brain lymphoma in AIDS patients

目的探讨12例艾滋病患者脑内淋巴瘤的特点。方法回顾性分析12例经手术和病理证实的艾滋病相关脑内淋巴瘤的CT及MRI资料,并结合文献复习。结果 12例淋巴瘤中,病灶单发5例,多发7例。其中位于幕上10例,幕下1例,幕上下多发1例。CT及MRI表现为实性、囊实性肿块;多发不规则片状病灶;沿脑室、脑膜匍匐状分布。结论 AIDS相关脑内淋巴瘤影像特点有其相对特异性,但少数易与弓形体脑炎等病变混淆,影像诊断必须结合临床并全面分析。

[Objective ] To investigate the CT and MRI features of brain lymphoma in 12 AIDS patients. [Methods] CT and MRI features of 12 cases which proved by surgery and pathology were retrospectively analyzed. [Results] Of all 12 cases, there were 5 cases which were found single lesion, 7 cases were multiple lesions, 10 cases were found in cerebral hemispheres, 1 in posterior fossa and 1 was found in ＇cerebral hemispheres and posterior fossa. The lesions on CT and MRI showed solid or cyst-solid masses, multiple irregular flake lesions, distributive lesions along the ventricle and meninges. [ Conclusion ] There were particular imaging characteristic of the brain lymphoma in the patients of AIDS, but a few still be confused with other disease such as toxoplasmosis. The diagnosis of the imaging must be combined with clinic.