妊娠妇女阴道微生态状况研究

Research of the vaginal microecology in pregnant women

目的:探讨不同妊娠期妇女的阴道微生态状况及影响阴道微生态的相关因素。方法:选取健康妊娠期妇女91例,进行问卷调查,采集阴道分泌物和脱落细胞,进行阴道微生态评价。结果:不同孕期妊娠妇女之间阴道pH值、乳酸杆菌优势率、致密核指数差异无统计学意义;妊娠期健康妇女阴道pH值与阴道上皮细胞致密核指数(KI)负相关,与乳酸杆菌优势率负相关;与阴道pH值相关的因素有年龄、产次、既往阴道炎病史及性伴侣文化程度;与阴道乳酸杆菌优势率有关的因素有年龄、产次及性伴侣文化程度;16例无阴道自觉症状、阴道清洁度正常的"健康"妊娠期妇女,微生态评价处于失调状态。结论:不同妊娠期健康妇女脱落细胞致密核指数、乳酸杆菌优势率、阴道pH值无明显差异;妊娠期妇女阴道微生态的影响因素有年龄、产次、既往阴道炎病史及性伴侣文化程度。

Objective： To evaluate vaginal microecology state and its related factors of the pregnancy woman. Methods： About 91 vaginal healthy women were conducted with a questionnaire Vaginal discharge and cast - off were collected to get the microecology evaluation. Results ： The differences of vaginal pH, the dominant rate of laqctobacillus and karyopyknotic index （KI） were not statistically significant in different period of pregnant women. The vaginal pH was negatively related with KI and the dominant rate of laqctobacillus ; the vaginal pH was related to age, parity, formerly vaginitis history and sex partner~ culture level. The dominant rate of laqctobacillus was relat- ed to age, parity and sex partner~ culture level. Sixteen women who were vaginal healthy and without vaginal symptom were found in micro- ecology disturbance. Conclusion： There is no difference in the vaginal cast - off karyophknotic index, the dominant rate of laqctobacillus and the vaginal pH in different period of pregnant women. The microecology in pregnancy is related to the age, parity, formerly vaginitis history and sex partner＇s culture level.