中国2003--2007年甲状腺癌发病死亡现状及流行趋势分析

Trend of incidence and mortality on thyroid cancer in China during 2003-2007

目的分析中国甲状腺癌发病和死亡现状及流行趋势。方法2003--2007年甲状腺癌发病和死亡数据来源于全国32个肿瘤登记处，分别计算粗率、年龄别发病率和死亡率、中国人口标化率（中标率）和世界人口标化率（世标率）及变化趋势；采用Jionpoint模型对部分登记地区的20年发病和死亡数据进行趋势分析。结果2003--2007年中国甲状腺癌发病率为4．44／10万，中标率为2．89／10万，世标率为3-31／10万；甲状腺癌死亡率为0．44／10万，中标率0．21／10万，世标率0．29／10万，分别占恶性肿瘤发病死亡构成的1．67％和0．26％；女性发病率和死亡率明显高于男性，分别为男性的3．38倍和1．75倍；城市人群发病率和死亡率高于农村；2003--2007年中国甲状腺癌发病率和死亡率呈上升趋势，每年分别以14．51％和1．42％的速度上升。结论中国甲状腺癌发病率和死亡率均呈上升趋势，应有效控制其高发现状。

Objective To analyze the trend of incidence and mortality on thyroid cancer in China. Methods Data from 32 cancer registry sites in China was collected and Jionpoint model was used to obtain the crude, age-specified incidence and mortality, both Chinese national and world age- standardized rates of incidence and mortality and their trends. Results The crude incidence of thyroid cancer was 4.44/105, and the Chinese national and world age-standardized rates were 2.89/105 and 3.31/105 respectively. The crude mortality of thyroid cancer was 0.44/105, with the Chinese national and world age-standardized rates as 0.21/105 and 0.29/105 during 2003-2007 in the country. Thyroid cancer accounted for 1.67% and 0.26% of the Chinese national and world age- standardized proportions, for total cancers. Both incidence and mortality of thyroid cancer were higher in females than in males, 3.38 and 1.75 times higher in urban areas than those in rural areas. The incidence of thyroid cancer showed annually increase of 14.51% while the mortality had an increase of 1.42%. Conclusion The incidence and mortality of thyroid cancer increased rapidly in China, calling for more control efforts on this disease.