摘要
目的:优选当归芍药散的提取工艺。方法:以芍药内酯苷、芍药苷、阿魏酸、23-乙酰泽泻醇B为评定指标,用多指标综合评分法进行数据处理,选取提取时间、提取次数、乙醇体积分数及乙醇用量为考察因素,采用正交试验优化提取条件。结果:最佳提取工艺为加8倍量75%乙醇回流提取2次,每次1.5 h。结论:该提取工艺稳定、合理,有效成分提取率高。
Objective：To optimize extraction conditions of Danggui Shaoyao powder.Method：With the content of albiflorin,paeoniflorin,ferulic acid and 23-acetate alisol B as indexes,test data was handled by multiple-index comprehensive scoring method,orthogonal test was adopted in optimizing extraction technology with extraction time,extraction times,the concentration of ethanol and ethanol volume as factors.Result： Optimized extraction technology was：extracted 2 times with 8 times the amount of 75% ethanol,1.5 h per time.Conclusion：This optimized extraction technology was rational and stable with high yield of active components.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第19期20-23,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金面上项目(81173368)
安徽省高校自然科学研究重点项目(KJ2010A213)
关键词
当归芍药散
芍药内酯苷
芍药苷
阿魏酸
23-乙酰泽泻醇B
正交试验
综合评分法
Danggui Shaoyao powder
albiflorin
paeoniflorin
ferulic acid
23-acetate alisol B
orthogonal test
multi-index comprehensive scoring method
