Z-综合评分法优化葛粉速溶颗粒制备工艺

Optimization of Preparation Technology for Gefen Instant Granule by Z-comprehensive Scoring Method

目的:探讨和优化葛粉速溶颗粒的制备工艺。方法:采用正交试验,选取糖粉-葛粉比例、泡打粉-葛粉比例、干燥温度为考察因素,以颗粒溶化时间和颗粒中总黄酮含量为指标,用Z-综合分析法优选制备工艺。按优选工艺制备3批样品,考察其性状、水分含量、溶化性及糊化试验等。Al(NO3)3显色法测定总黄酮含量。结果:最佳制备工艺为等量递增法往研钵中依次加入泡打粉1.2 g,糊精1.8 g,糖粉24 g和葛粉33 g混合均匀,加约5 mL温水(35～40℃)混匀,捏成团块状,在35℃环境下放置40 min,使其内部充满多而密的孔洞,体积膨大,质地松软,挤压过筛(10～14目),60℃干燥40 min,整粒,即得葛粉速溶颗粒。制得3批样品,大小均匀,呈乳白色,色泽一致,无吸潮、结块、潮解现象,溶化性试验合格,85℃左右热水冲溶全部糊化。颗粒水分含量<6.0%,总黄酮含量0.327 mg.g-1。结论:葛粉速溶颗粒的制备工艺简便可行、稳定,总黄酮含量测定方法可用于其质量评价。

Objective：To investigate and optimize preparation technology of Gefen instant granule.Method：With dissolution time and the content of total flavonoids of this granule as indexes,ratio of sugar-Pueraria lobata,ratio of baking powder-P.lobata,drying temperature were chosen as investigation factors,preparation technology was optimized by orthogonal test with Z-comprehensive analysis method.Three samples were prepared by optimized technology,and their properties,melting,water content and pasting test were investigated.The content of total flavonoids was determined by aluminum nitrate chromomeric method.Result：The best preparation process was as follows：uniform mixed baking powder 1.2 g,dextrin 1.8 g,sugur 24 g,and P.lobata 33 g sequentially by equal increment method,mixed evenly with about 5 mL hot water（35-40 ℃）,shaped into lump,placed at environment of 35 ℃for 40 min to make its interior with multiple and dense holes,volume expansion and soft texture,squeeze sieved,dried at 60 ℃ for 40min,arranged granules,and then Gefen instant granule were gained.Prepared 3 batches of samples had uniform size,milky white,color consistency,no absorption of moisture,agglomeration and phenomenon of deliquescence.Melting test qualified,it dissolved completely at about 85 ℃ in hot water.The moisture content was less than 6.0%,and the content of total flavonoids was 0.327 mg · g-1.Conclusion：This optimized preparation technology was simple,feasible and reproducible,and the content of total flavonoids determination method was suitable for quality control of Gefen instant granule.