康艾注射液对胃肠癌化疗患者的临床随机对照研究

Randomized controlled clinical trial of Kang'ai injection in gastrointestinal cancerchemotherapy patients

目的:研究康艾注射液对胃肠癌化疗患者的生活质量的影响。方法:将42例胃肠癌患者随机分为治疗组(n=22)对照组和(n=20)。治疗组用康艾注射液加化疗,并与单纯化疗组进行对照。观察治疗后的生活质量、评价临床症状改善情况及不良反应。结果:治疗组与对照组疾病控制率分别为91%,30%,KPS提高率分别为59%,30%,Ⅲ°以上不良反应,分别为1例和6例,经比较差异有统计学意义。结论:康艾注射液可改善胃肠癌化疗患者症状,提高生活质量,对化疗有减毒增效的作用。

Objective ： To study the influence of Kang＇ai injection on quality of life among gastrointestinal cancer chemotherapy patients. Method： Fourty-two gastrointestinal cancer patients were randomly divided into the treatment group （n = 22 ） and the control group （n = 20）. The treatment group was treated with chemotherapy and Kang＇ai Injection, and the control group was only treated with chemotherapy. Their quality of life, improvement of clinical symptoms and adverse effects were observed. Result： The disease control rates of the treatment group and the control group were 91% and 30% ,while their effective rates of KPS were 59% and 30% respec- tively. They had one case and six cases with side effects above Ⅲ° Conclusion： Kang＇ai Injection can mitigate syndromes of gastroin- testinal cancer chemotherapy patient,improve their quality of life and have an effect of reducing toxic and enhancing efficacy for chenlo- therapy.