摘要
中药复方物质基础是多组分,在研究中药生物药剂学性质时,应该以组分为研究对象。针对中药多组分生物药剂学研究,该文提出科学代表中药组分综合性质的有限成分的选择思路;其次,引入"离散度"的概念,以考察组分中各代表性成分个体性质之间的差异,从而更科学全面地评价中药组分的性质;最终结合组分综合性质值及离散度,初步构建中药组分生物药剂学分类系统,为中药多组分生物药剂学性质研究提出新的思路与方法。
Traditional Chinese medicine compound of material base is muhi-components. It should be divided into groups to study traditional Chinese medicine biopharmaceutical properties. To study traditional Chinese medicine muhi-compouent biopharmaceu- tieal, this paper puts forward the scientific representative Chinese medicine integrated nature of the components of the composition, choose ideas. Secondly, this paper introduces the concept of＂ ＂ discrete degree＂ to examine difference about representative nature ~ff each component. It should be more comprehensive evaluation of traditional Chinese medicine scientific nature ~ff the components. With the comprehensive property value final components and discrete degrees, setting up a part of traditional Chinese medicine biopharma- eeutical classification system, traditional Chinese medicine for the multi-composition biopharmaceutical nature study puts forward a new way and method. [Key words] components; preparation design of traditional Chinese medicine; comprehensive properties expression; discrete degree; bioavailability classification system
出处
《中国中药杂志》
CAS
CSCD
北大核心
2012年第19期2997-3000,共4页
China Journal of Chinese Materia Medica
基金
江苏省中医药领军人才专项(2006)
江苏省中医药局中医药科技技术研究专项(LZ09061)
关键词
组分
中药制剂设计
综合性质表达
离散度
生物药剂学分类系统
components
preparation design of traditional Chinese medicine
comprehensive properties expression
discretedegree
bioavailability classification system
