摘要
目的:优选老鹳草巴布剂基质配方。方法:以成型巴布剂的黏着力、赋型性、综合感官为综合评价指标,选取NP700、酒石酸、PVP-K90、甘羟铝为考察因素,采用L9(34)正交设计法评定不同材料配比下巴布剂的性能。结果:最佳基质配方为NP700-酒石酸-PVPK90-甘羟铝7.5∶0.4∶3∶0.05。结论:该巴布剂配方合理稳定,且性能较好。
Objective： To optimize matrix formulation of Geranium wilfordii cataplasm. Method： With adhesive force, shapability and general sensory as comprehensive evaluation index, ratio of NPT00, tartaric acid, PVP-K90 and dihydroxy alumimun aminoacetate were chosen as investigated factors, L9 （34） orthogonal experiment was used to evaluate properties of cataplasm with different materials ratio. Result： Optimum matrix formulation of cataplasm was NP700-tartaric acid-PVP K90-dihydroxy alumimun aminoacetate 7.5： 0.4： 3： 0.05. Conclusion： This optimized formulation was feasible and stable with better performance.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第20期52-54,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
巴布剂
基质
正交试验法
老鹳草
cataplasm
matrix
orthogonal experiment
Geranium wilfordii
