摘要
目的:优选苦参提取工艺参数。方法:以苦参总生物碱和干膏率为考察指标,单因素试验考察提取溶媒、溶媒pH;采用正交试验法,选取溶媒用量、提取时间、提取次数为考察因素,以苦参总碱总量和固含物总量的总权重为考察指标,优选苦参提取工艺。结果:优选的提取工艺为加0.2%盐酸溶液提取3次,每次加6倍量溶媒,每次提取2 h。结论:该优选工艺稳定可行,可用于苦参的工业化提取。
Objective： To optimize extraction ]3rocess parameters of Sophorae flavescens. Method ： With total alkaloids from S. flavescens and dry extract as indexes, extraction solvent and pH of solvent were investigated by single factor test ; With total weight of the content of total alkaloids and solid as indexes, Orthogonal design was used to investigate effect of solvent consumption, extraction time, extraction times on extraction process. Result： Optimal extraction process was： extracted 3 times with 6 times the amount of 0.2% hydrochloric acid, 2 hours each time. Conclusion： This optimized technology was stable and feasible, it could be used to industrial extraction of S. flavescens.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第20期58-60,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
成都大学开放实验室项目
关键词
苦参
滴定法
苦参总生物碱
提取工艺
Sophora flavescens
titration
total alkaloids from S. flavescens
extraction process
