海州常山的化学成分与药理作用研究

Study Advancement about Chemical Composition and Pharmacological Action of Clerodendron trichotomum

总结海州常山在化学成分和药理作用方面的研究进展,为海州常山进一步开发提供参考。查阅CNKI,MEDLINE和CA等主要数据库中有关海州常山在化学成分和药理作用方面的文献各16,10,7篇,并进行汇总、分析和评述。化学成分方面共发现119个挥发性化合物、8个黄酮化合物、14个苯丙素类化合物、1个糖苷和3个生物碱类化合物;药理方面主要有降压、抗炎、抗氧化、镇痛、镇静、抗细胞增殖和抗艾滋病病毒作用。海州常山化学成分和药理作用中与大极性成分有关的研究较多,但中等及小极性成分的研究较少,建议加强中等偏小极性成分的研究,为建立海州常山质量标准及深度开发奠定基础。

To summarize the research progress on chemical components and pharmacological actions of Clerodendron trichotomum and provide useful references for the further research. All papers about chemical components and pharmacological actions in CNKI, MEDLINE and CA databases etc were referred to and summarized. The chemical components isolated from C. trichotomum, include mainly essential oil, flavone, phenylpropanoids, glucoside and alkaloids; Pharmacological references show that it has depressurization, anti- inflammation, anti-oxidation, analgesia, mitigate, anti-cell multiplication and anti-HIV. The studies about big heteropolarity components which related with chemical and pharmacological have been reported more, however, the moderate and small heteropolarity components were researched lessly, we should carry out further studies on moderate and small heteropolarity components, to establish foundation for C. trichotomum＇ quality criteria and deep development.