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微小RNA在肺部疾病中的研究进展

New research advance of microRNA in lung diseases
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摘要 微小RNA（miRNA）是一种内源性的单链小分子非编码RNA，它在不同组织中的表达水平差异很大，最新的研究发现，miRNA在细胞的分化、增殖、凋亡中起重要的调节作用，miRNA的调节异常可导致疾病的发生。本文就近年来对miRNA在肺部疾病方面中的研究进展进行简要综述。 MiRNA are endogenous and no coding RNA, and their expression levels vary greatly among tissues, recent studies have indicated that miRNA are critical regulators of widespread cellular functions such as differentiation, proliferation, and apotosis, and dysregulation of miRNA can contribute to disease pathology. In this paper we will discuss their roles in lung diseases according to the latest researches.
作者 胡红玲 赵苏
机构地区 武汉市中心医院呼吸内科
出处 《国际呼吸杂志》 2012年第19期1514-1516,共3页 International Journal of Respiration
关键词 微小RNA 基因表达 MiRNA模拟 Micro RNA Gene expression MiRNA mimics
分类号 R563 [医药卫生—呼吸系统]
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参考文献19

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国际呼吸杂志
2012年 第19期

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