两种β-环糊精衍生物混合GC固定相的研究

Investigation on the GC Mixed Stationary Phase of Two Cyclodextrin Derivatives

研究两种 β-环糊精衍生物 (全甲基 - β- CD与七 - (2 ,6 -二 - O-戊基 - 3- O-烯丙基 ) - β-CD)混合 GC固定相的分离性能 .用毛细管气相色谱法研究苯的位置异构体在两种环糊精混合固定相上的分离情况 ,从柱效、固定相的结构及其与溶质的作用方式讨论两种环糊精混合固定相的分离机制 .所测试的大部分苯位置异构体在混合固定相柱上均能得到较好的分离 ,其中溴甲苯等位置异构体在混合固定相上的分离因子偏离加和效应 ,出现了协同效应 .两种

The GC separation properties of the mixed stationary phase of two cyclodextrin derivatives (permethy1 β cyclodextrin and heptakis(2,6 di O pentyl 3 O allyl) β cyclodextrin) were studied using benzene positional isomers. The separation mechanism on mixed stationary phase was discussed from column efficiency, structure of stationary phase and the interaction mode between stationary phases and solute. Most of positional isomers of disubstituted benzene were well separated on the mixed stationary phase column, with the separation of bromotoluene, nitrotoluene etc. on the mixed stationary phase column demonstrating synergistic effects. The GC properties of the mixed stationary phase of two cyclodextrin derivatives are different from that of the conventional mixed stationary phases.