不同组分、不同纯度中药复方多糖对小鼠血液指标的影响

Research on Chinese Medicinal Compound Polysaccharide's Influence on Mice Blood Index with Different Components and Different Degrees of Purity

本试验旨在观察不同组分、不同纯度中药复方多糖对小鼠血液指标的影响。选用环磷酰胺造成小鼠免疫抑制模型,灌服不同组分、不同纯度中药复方多糖、复方总多糖和复方水煎剂,测定它们对小鼠外周血象的影响。结果表明A2多糖组分、B2纯度多糖、复方总多糖、复方水煎剂均能使小鼠红细胞数、白细胞数、白细胞分类数中的嗜中性粒细胞百分比、淋巴细胞百分比明显升高,与模型组比较有极显著性差异(P<0.01)。A2多糖组分、B2纯度多糖、复方总多糖、复方水煎剂可改善环磷酰胺所致小鼠血液参数减少的外周血象,调节免疫失衡。

This experiment aims to investigate Chinese medicinal compound polysaccharide＇ s （CMCP） influence on mice blood index with different components and different degrees of purity. In our experiment firstly we select cyclophosphamide to build mice immunity-inhibition model and then we respectively gavage CMCP with different components and different degrees of purity, compound total polysaccharide and compound water decoction into mice to measure their effects on mice＇s peripheral hemogram. The result shows that polysaccharide A2, purity polysaccharide B2, compound total polysaccharide and compound water decoction can significantly increase the number of erythrocytes, the number of leukocytes, neutrophilic granulocyte＇s percentage in leukocyte classification number and the percentage of lymphocytes in mice. The result also shows a very signifi- cant difference from the model group （P〈0.01）. Therefore it can be seen that polysaccharide A2, purity polysaccharide B2, compound total polysaccharide and compound water decoction can improve reduced peripheral hemogram in mice blood index, which is caused by cyclophosphamide, to regulate immune imbalance.