同层面的辨证模式是探索疾病证型规律的关键——从PCOS不同中医证型规律的研究中启示

The Chinese medicine syndrome typing mode at the same level is the key point to explore the syndrome laws of disease——An inspiration from studying Chinese medicine syndrome laws of polycystic ovarian syndrome

中医辨证方法不仅为疾病的诊断与治疗提供信息,也体现疾病发生与转归的全过程。规范的辨证方法为临床疗效评估与科研工作提供了检验的平台。笔者经过16年的临床探索,将多囊卵巢综合征(polycystic ovarian syndrome,PCOS)不同中医证型患者在同一辨证层面(生殖内分泌代谢)上进行组间比较,并与健康人进行对照,结果发现PCOS不同中医证型患者在生殖内分泌代谢特征方面存在同质性和异质性。这对了解PCOS病理变化与证型之间的规律有重要意义,对理解和阐明中医学理论中相关脏腑虚证与PCOS的关系具有很好的启示。因此认为,在同层面的辨证模式下,探索疾病各证型的规律,从中寻找疾病发生机理,这样才能有效地提高中西医结合的临床疗效和科研水平。

Chinese medicine （CM） syndrome typing methods not only provides information on the diag- nosis and treatment of diseases, but also embodies the whole process of their occurrence, development, and prognosis. Standard syndrome typing methods can provide a testing platform for clinical efficacy assessment and scientific research work. By my 16 years＇ clinical experience, inter-group comparison of polycystic ovarian syn- drome （PCOS） patients of different CM syndrome types at the same level （reproductive endocrinology and me- tabolism） was conducted. They were also compared with the healthy subjects. Results showed that homogeneity and heterogeneity exist in PCOS patients of different CM syndromes in the reproductive endocrine and metabolic characteristics, which is important to understand the laws between the pathological changes and syndrome types of PCOS. It is also a good inspiration to understand and clarify the correlation between the asthenia of Zang-Fu organs in CM theories and PCOS. Therefore, I believe that it is necessary to explore the laws of each CM syn- drome type at the same level of syndrome typing, thus finding out the pathogenesis of PCOS. Only in this way could the clinical efficacy and the research level of integrative medicine be effectively improved.