地佐辛与曲马多防治丙泊酚注射痛的应用体会

目的:观察地佐辛与曲马多在防治丙泊酚注射痛的可行性与安全性。方法:120例ASAⅠ～Ⅱ级择期全麻患者,随机分为3组。每组患者在注射丙泊酚前5min分别注射0.9%生理盐水(A组);0.1mg/kg地佐辛(B组);2mg/kg曲马多(C组),均稀释为5ml。观察静注丙泊酚的疼痛发生率及严重程度。结果:B、C组注射痛的发生率明显低于A组(P<0.05)。B、C组的中重度疼痛明显低于A组(P<0.01)。结论:0.1mg/kg地佐辛与2mg/kg曲马多可减少丙泊酚注射痛的疼痛程度。

Objective： Observed to dezoeine and tramadol in the prevention of propofol injection pain feasibility and security. Method： 120 cases of ASA Ⅰ-Ⅱ elective anesthesia patients＇, Were randomly divided into 3 groups. Each group of patients before the injection of propofol were injected with 0. 9% saline （A group） 5min; 0. lmg/kg dezocine（B group）;2mg/kg Tramadol（C group） were diluted for 5ml. Observe the incidence of pain and severity of intravenous propofol. Results： B, C group was injected with pain were significantly lower in group A;B, C groups was not statistically significant. B, C group moderate to severe pain was significantly lower in group A （P〈0. 01）. Conclusion：0. 1mg/kg dezocine and 2mg/kg Tramadol can reduce the incidence of propofol injection pain, and effectively reduce the extent of pain.