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黑升麻提取物治疗子宫内膜癌患者术后绝经症状的临床研究 被引量:4

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摘要 目的观察黑升麻提取物(莉芙敏)用于子宫内膜癌患者术后绝经期症状治疗的安全性和有效性。方法35例手术后出现绝经症状服用莉芙敏半年的患者为观察组,同期就诊的40例没有使用莉芙敏或其他HRT(激素替代疗法)治疗的患者为对照组,比较两组患者治疗前后的KMIf绝经指数评分)及全身骨密度,评价莉芙敏的疗效。观察两组患者治疗前后的性激素水平、CA125等指标,评价莉芙敏治疗的安全性。结果观察组服用莉芙敏半年后,绝经症状明显改善,KMI评分显著下降,与治疗前相比有显著差异(P〈0.05),全身骨密度维持稳定;对照组经半年观察后,KMI评分没有明显变化(P〉0.05),全身骨密度有所下降(P〈0.05)。所有患者性激素水平、CA125水平没有明显变化(P〉0.05)。在随访的1年内,两组患者各有2例肿瘤盆腔内复发,其中对照组2例复发患者死亡,观察组1例复发患者死亡,患者死亡原因均为肿瘤复发。结论莉芙敏用于子宫内膜癌患者术后绝经症状治疗安全有效。
作者 黎晓霞
出处 《国际医药卫生导报》 2012年第20期2977-2979,共3页 International Medicine and Health Guidance News
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参考文献8

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