新生儿低血糖相关因素分析

Study on the relevant factors of neonatal hypoglycemia

目的探讨新生儿低血糖的相关因素及其临床特点，为临床诊治提供依据，制定良好的防治方案，避免发生新生儿低血糖症及低血糖性脑病等严重并发症，提高患儿日后生活质量。方法2010至2012年在我院儿科住院符合新生儿低血糖诊断标准的患儿连续入选为研究对象，共收集有效病例80例，同时收集同期血糖正常的新生儿80例，对其进行回顾性分析，分别测定、记录人选对象血糖及基本临床特征、围产期情况、出生情况与常见新生儿合并症等指标，进行统计，分析新生儿低血糖的危险相关因素。结果新生儿低血糖的危险相关因素为孕母妊娠期高血压、妊娠期糖尿病、早产儿、小于胎龄儿、双胎或多胎、日龄≤3天、低出生体重儿、新生儿窒息等。结论对存在高危因素的新生儿，应及早监测血糖，及时干预，以预防临床新生儿低血糖及低血糖性脑损伤的发生及再发生。

Objective To investigate the relevant factors of neonatal hypoglycemia and the clinical features, to provide the basis for clinical diagnosis and treatment. Methods All 80 newborns with hypoglycemia in department of neonatal intensive care unit （NICU） of Jiangmem Central Hospital were consecutively recruited from 2010 to 2012. Other 80 orthoglycemic newborns in NICU were included in the study to characterize their clinical features, perinatal condition, birth condition and common neonatal complications. Laboratory tests included blood glucose. Results The relevant factors of neonatal hypoglycemia were hypertensive disorders in pregnancy, gestational diabetes mellitus, preterrm infant, Small for gestational age infant, twins or multiple births, day-old ≤ 3 days, low birth weight infant and asphyxia of newboru.eondusions For the newborn with risk factors, they should be monitored with blood glucose and intervened eMy, to prevent neonatal hypogly- cemia and incidence and reoccurrence of brain injury,