体外反搏治疗对失眠患者脑血流变化情况的临床研究

The Clinical Research of Effect of External Counterpulsation Therapy on Cerebral Blood Flow of Patients with Insomnia

目的探讨体外反搏治疗对失眠患者睡眠质量及脑血流变化情况的影响.方法 90例失眠患者随机分为治疗组45例和对照组45例,2组均按内科常规药物进行治疗,治疗组在常规治疗的基础上加体外反搏治疗,对照组只采用常规治疗,14 d为一个疗程,治疗1个疗程后复查经颅多普勒脑血流图.结果体外反搏治疗前后2组之间比较LMCA、RMCA、LVA、RVA平均流速变化有明显差异(P<0.05),RMCA、BA阻力指数变化有明显差异(P<0.05);治疗组45例中痊愈5例、显效18例、有效16例、无效6例,总有效率86.67%;对照组45例中痊愈1例、显效9例、有效24例、无效11例,总有效率75.56%,两组比较P<0.01,有显著性差异,治疗组疗效优于对照组.结论体外反搏治疗组和对照组均能有效改善失眠患者的睡眠率和临床症状,但治疗组优于对照组;体外反搏治疗失眠的机理与改善失眠患者的脑血流状况有关.

Objective To explore the effect of external counterpulsation therapy on quality of sleep and cerebral blood flow of patients with insomnia.Methods Ninety patients with insomnia were randomly divided into the treatment group control group,45 cases in each group.Patients in two groups were given the conventional drug treatment in Department of Internal medicine.Besides the conventional drug treatment,patients in the treatment group were also given external counterpulsation treatment,and patients in control group were not given other treatment.The course of treatment was 14 days,and after 1 course of treatment,the cerebral blood flow of patients were rechecked by transcranial Doppler ultrasonography.Result The therapeutic effect of the treatment group was superior to control group after external counterpulsation treatment,and the difference was statistically significant（P 〈0.01）.Conclusions Both external counterpulsation treatment plus routine treatment and only routine treatment can improve the sleep quality an clinical symptoms of patients with insomnia,but the formal treatment has better effect.The mechanism of external counterpulsation for the treatment of insomnia is related with improving the cerebral blood flow of patients.