B超、CT及MRI检查在视网膜母细胞瘤诊断中的价值

Value comparison of type-B ultrasound,CT and MRI examination in diagnosis of retinoblastoma

目的比较B超、CT及MRI检查在视网膜母细胞瘤诊断中的价值。方法选择2010年4月至2011年10月在我院进行检查治疗的视网膜母细胞瘤患者130例(195眼),采用B超检查者71例(99眼)、CT检查者42例(70眼)、MRI检查者17例(26眼),记录各组的图像特点以判断肿瘤分期,并将各组的检查结果与病理学诊断结果进行对比分析。结果行B超、CT及MRI检查患者中,分别有82眼(82.8%)、35眼(50.0%)、11眼(42.3%)显示有钙化斑,13眼(13.1%)、21眼(30.0%)、3眼(11.5%)显示视神经增粗,3眼(3.0%)、6眼(8.6%)、8眼(30.8%)提示肿瘤向眶内蔓延,差异均有统计学意义(均为P<0.05)。行B超、CT及MRI检查患者中,分别有83眼、53眼、15眼显示为Ⅰ期,13眼、11眼、3眼为Ⅱ期,3眼、6眼、8眼为Ⅲ期,与病理学检查分期改变相符合分别为25眼(25.3%)、27眼(38.6%)、4眼(15.4%),差异均有统计学意义(均为P<0.05)。结论 B超、CT及MRI检查在视网膜母细胞瘤诊断中各有其优势之处,应根据患者的具体病情,注重联合检查,以提高诊断的正确率。

Objective To compare the value of type-B ultrasound,CT and MRI examination in the diagnosis of retinoblastoma.Methods From April,2010 to October 2011,130 patients （195 eyes） with retinoblastoma were received type-B ultrasound examination （71 cases,99 eyes）,CT examination （42 cases,70 eyes） and MRI examination （17 cases,26 eyes）,respectively.The characteristics of images were recorded to determine the stage in each group,the results were compared with pathologic diagnosis,and then the statistical analysis was made.Results In patients with type-B ultrasound,CT and MRI examination,the calcified plaque appeared in 82 eyes （82.8%）,35 eyes （50.0%） and 11 eyes （42.3%）,respectively,optic nerves augmentation appeared in 13 eyes （13.1%）,21 eyes （30.0%） and 3 eyes （11.5%）,respectively,tumor breaking into orbit appeared in 3 eyes （3.0%）,6 eyes （8.6%） and 8 eyes （30.8%）,respectively,there were statistical differences （all P0.05）.In patients with type-B ultrasound,CT and MRI examination,there were 83 eyes,53 eyes and 15 eyes in stageⅠ,13 eyes,11 eyes and 3 eyes in stageⅡ,3 eyes,6 eyes and 8 eyes in stage Ⅲ,which accorded with the pathologic stage were 25 eyes （25.3%）,27 eyes （38.6%） and 4 eyes （15.4%）,there were statistical differences （all P0.05）.Conclusion In the examinations of type-B ultrasound,CT and MRI for the diagnosis of retinoblastoma,each one has its advantages.According to their conditions,we should pay attention to the combined examination in order to improve diagnostic accuracy.