蛋白质组学技术用于晶状体蛋白的研究进展

he progress of proteomics approaches in cataract research

近年来，晶状体蛋白质组学的相关研究日渐广泛。蛋白质组学技术以其高通量、高效率等优势，为晶状体这一人体内蛋白质含量最高组织的蛋白质组学研究提供了可靠的技术支撑，从而为揭示年龄相关性白内障的发生机制提供了新思路和新方向。本文就蛋白质组学的分离、鉴定及相关新技术在晶状体蛋白研究中的应用进展做一系统综述。（中华腠科杂岙，2012，48：952—955）

Researches on lens proteomics are becoming prevalent in recent years. Characterized by their high resolusion and efficiency, proteomics approaches provide reliable methodological support for lenses proteomic research, which demonstrates a new orientation for revealing the mechanism of cataractogenesis. This review outlines the separation, identification and some novel approaches of proteomic techniques applied in recent lenses proteomie research. （Chin J Ophthalmol , 2012,48：952-955 ）