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环境因素与运动干预诱导表观遗传修饰改变与疾病易感性的关系 被引量：2

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摘要 经济发展引起的生活方式改变已导致我国居民肥胖、胰岛素抵抗（Insulin Resistance，IR）和2型糖尿病（Type2 Diabetes．T2DM）等代谢性疾病发病率激增．成为影响我国人口健康和生活质量的主要危险因素之一。
作者 刘素 牛燕媚 傅力
机构地区 天津医科大学康复与运动医学系
出处 《中国运动医学杂志》 CAS CSCD 北大核心 2012年第9期844-848,822,共6页 Chinese Journal of Sports Medicine
基金 国家自然科学基金(31100856)
关键词 表观遗传修饰 疾病易感性 环境因素 预诱导 运动 胰岛素抵抗 2型糖尿病 疾病发病率
分类号 G804.2 [文化科学—运动人体科学] R394 [医药卫生—医学遗传学] R87 [医药卫生—运动医学]
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参考文献60

  • 1Rosenbloom AL,Silverstein JH,Amemiya S,et al. Type 2 diabetes in the child and adolescent. Pediatric Diabetes, 2009,10(12) :S17-S32.
  • 2Lillycrop KA. Symposium 1 :Nutrition and epigenetics Effect of maternal diet on the epigenome :implications for human metabolic disease. Proceedings of the Nutrition Society, 2011,70( 1 ) : 64-72.
  • 3Skinner MK. Role of epigenetics in developmental biology and transgenerational inheritance. Birth Defects Research (Part C) ,2011,93(1) :51-55.
  • 4Hussain N. Epigenetic influences that modulate infant growth,development and disease. Antioxid Redox Signal, 2012,17(2) :224-236.
  • 5程学美,单宝德,张天亮.环境与表观遗传学[J].职业与健康,2010,26(18):2136-2138. 被引量：2
  • 6Klose RJ,Bird AP. Genomic DNA methylation:The mark and its mediators. Trends Biochem Sci,2006,31 (2):89- 97.
  • 7Jenuwein T,Allis CD. Translating the histone code. Science ,2001,293 (5532) : 1074-1080.
  • 8Calle A,Femandez-Gonzalez R,Ramos-Ibeas P,et al. Long-term and transgenerational effects of in vitro culture on mouse embryos. Theriogenology,2012,77(4):785-793.
  • 9Vickaryous N,Whitelaw E. The role of early embryonicenvironment on epigenotype and phenotype. Reprod Fertil Dev, 2005,17 (3) : 335-340.
  • 10Vickaryous N,Whitelaw E. The role of early embryonic environment on epigenotype and phenotype. Reprod Fertil Dev, 2005,17 (3) : 335-340.

二级参考文献9

  • 1郭新红,刘文彬.表观遗传学及其研究进展[J].安徽农业科学,2007,35(1):9-10. 被引量：4
  • 2Collins FS, Morgan M, Patrinos A. The human genome project: lessons fromlarge-scale biology[ J]. Science ,2003,300:286 - 290.
  • 3Palmisano WA, Divine KK, Saccomanno G, et al. Predicting Lung Cancer by Detecting Aberrant Promoter Methylation in Sputum. Cancer Res, 2000:5954 - 5958.
  • 4Pereira MA, Kewa L, Kramer PM. Promotion by mixtures of dichloroacetic acid of N2methyl2N2nitrosourea2 initiated cancer in the liver of female B6CBF1 mice[J]. Cancer Lett,1997,115:15 -23.
  • 5Fuks F, Hurd PJ, Wolf D, et al. The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation [ J ]. J Biol Chem,2003, 278:4035 -4040.
  • 6Reira MA, Kramer PM, Conran PB, et al. Effect of chloroform on dichloroacetic acid and trichloroacetic acid - induced hypomethylation and expression of the c2myc gene and on their promotion of liver and kidney tumors in mice [ J ]. Carcinogen, 2001,22 : 1511 - 1519.
  • 7Pepreira MA, Wei W, Kramer PM, et al. Prevention by methionine of dichloroacetic acid2induced liver cancer and DNA hypomethylation in mice[ J] Toxicol Sci ,2004,77:243 - 248.
  • 8Tao L, Wang W, Li L, et al. DNA hypomethylation induced by drinking water disinfection by products in mouse and rat kidney[ J]. Toxieol Sci, 2005,82:344 - 352.
  • 9庄志雄,纪卫东.环境表观基因组学相关技术[J].毒理学杂志,2007,21(5):346-350. 被引量：3

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中国运动医学杂志
2012年 第9期

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