摘要
随着组织工程的不断发展,已有多种工程化组织或器官如皮肤、骨、软骨等被成功研发并应用于临床,但血管化问题仍是组织工程发展和应用所面临的主要挑战之一。为了实现快速血管化的目标,各国学者对血管化进程、影响因素及相关机制进行了深入研究。
Rapid angiogenesis is one of the major issues in the fieht of tissue engineering, and it is an urgent problem to be solved. The process and related mechanism of angiogenesis have been deeply researched. Meanwhile, various methods or strategies for promoting angiogenesis, involving the applieation of stem cells and growth factors, and construction and modification of hiomalerial scaffolds, have also been reported. On one hand, many remarkable advances in the field of promoting angiogenesis have been achieved; on the other hand, the complexity of mech- anism and regulation of angiogenesis have gradually been recog- nized and emphasized. This paper presents a comprehensive overview of advances in research of the strategies for promoting angiogenesis in the field of tissue engineering.
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2012年第5期374-377,共4页
Chinese Journal of Burns
基金
浙江省自然科学基金(LQ12H15001)
浙江省重大科技专项(2007C0304)