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清除幽门螺杆菌感染干预肝性脑病的效价比分析

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摘要 目的观察清除幽门螺杆菌感染干预肝性脑病的成本-效果。方法将78例肝性脑病伴幽门螺杆感染患者分为观察组和对照组各39例,对照组门冬氨酸鸟氨酸降血氨等综合处理。观察组在综合处理的基础上予奥美拉唑、左氧氟沙星、阿莫西林口服清除幽门螺杆菌感染,疗程7d。观察肝性脑病的改善情况,抗幽门螺杆菌治疗前后检查血氨浓度。结果在综合处理的基础上给予奥美拉唑、左氧氟沙星、阿莫西林口服清除幽门螺杆菌感染,治疗7d后,观察组38例中总有效率为92.3%;对照组39例中总有效率为84.6%。两组总有效率差异无统计学意义(P>0.05)。应用最小成本分析法发现观察组产生单位效益的费用对照组少7.5元。结论奥美拉唑、左氧氟沙星、阿莫西林口服清除幽门螺杆菌感染干预肝性脑病效价比良好,经济安全,可供临床优先选择。
作者 陈扬
出处 《中国医药指南》 2012年第28期128-129,共2页 Guide of China Medicine
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