肾细胞癌的超微结构分型

Ultrastructural typing of renal cell carcinoma (RCC)

本文对30例肾细胞癌(包括16例透明细胞型,7例颗粒细胞型,1例梭形细胞型和6例透明细胞与颗粒细胞混合型)的超微特征进行了仔细的比较。在电镜下,透明细胞、颗粒细胞和梭形细胞之间除了脂滴、糖原和线粒体的数量有所不同之外,并无本质上的差异。因此,本文建议将肾细胞癌分为三个超微结构类型:富于脂滴和/或糖原型(透明细胞型),富于线粒体型(颗粒细胞型)和脂滴和线粒体贫乏型(梭形细胞型)。超微结构的分化程度可能具有预后价值。

30 cases ot RCC, including 16 clear, 1 spindle and 6 mixed (clear and granular), were carefully compared in their ultrastructural characteristics. The clear, granular and spindle cell type of RCC were not different in nature but rather in the quantity of lipid, glycogen and mitochondria present. So, ultrastructually, RCC may be classified into 3 types: that rich in lipid and/or glycogen (clear), that rich in mitochondria (granular) and that poor in lipid and mitochondria (spindle). It was also found that the degree in ultrastructural differention can be of value in prognosing the RCC.