标准大骨瓣开颅与常规骨瓣开颅治疗重型颅脑损伤的临床对照研究

Comparative study on Large trauma craniotomy and routine craniotomy in the treatment of severe traumatic head injury

目的比较大骨瓣开颅与常规骨瓣开颅治疗重型颅脑损伤的临床疗效。方法将122例重型颅脑损伤患者随机分为大骨瓣组62例采用大骨瓣开颅术治疗,和常规骨瓣组60例采用常规骨瓣开颅术治疗。比较两组术后疗效、颅内压变化、并发症的发生率。结果大骨瓣组在术后疗效上与常规骨瓣组比较,差异有统计学意义(P<0.05),在颅内压变化方面,大骨瓣组比常规骨瓣组降压效果好,有统计学意义(P<0.05)。并发症的发生率进行比较,两组差异无统计学意义(P>0.05)。结论大骨瓣开颅术比常规骨瓣开颅术减压效果更明显,疗效更好,值得临床使用。

Objective To compare the effects of Large trauma craniotomy and routine craniotomy in the treatment of severe traumatic head injury.Methods 122 cases with severe traumatic head injury were randomly divided into Large craniectomy group and the conventional Bone flap group,The former group include 62 cases,was large trauma craniotomy,The latter group include 62 cases,was fixed with routine craniectomy.Compare two groups of the postoperative curative effect and intracranial pressure changes and the complication rate.Results The differences between Large craniectomy group and the conventional Bone flap group were not statistically significant in the postoperative curative effect（P 0.05）.In intracranial pressure changes,Large craniectomy group has more antihypertensive effect than the conventional Bone flap group,which show statistic difference between two groups（P 0.05）.In the complication rate,no statistically significant differences between the two groups.Conclusion Large trauma craniotomy has more apparent antihypertensive effect and the postoperative curative effect than the conventional Bone flap group,which was worthy of clinical use.