透明质酸注射矫正泪槽畸形

Clinical application of hyaluronic acid on the treatment of tear through deformity

目的评价应用透明质酸（HA）注射矫正泪槽畸形的临床效果。方法自2010年6月至2012年6月，对35例矫正泪槽沟畸形患者进行HA注射治疗，注射剂量为0．5～1．5ml。观察注射后的临床效果、疗效时间、不良反应等。结果所有的注射部位均于注射后即刻得到改善。注射后随访患者，1、3、6个月分别有95．5％、84．7％、52．3％的注射部位维持了改善的效果；6～12个月有43．7％的注射部位维持了改善的效果；12-18个月有15．8％的注射部位维持了改善的效果。注射治疗中，未出现急慢性过敏反应及感染、肉芽肿、血管栓塞等并发症。结论HA作为暂时性填充剂，治疗泪槽沟畸形安全、可靠。

Objective To evaluate the clinical effects of hyaluronic acid （HA） on the treatment of tear trough deformity. Methods From June 2010 to June 2012, totally 35 patients with tear trough deformity re- ceived HA injection with a volume of 0.5-1.5 ml at various layers of soft tissues in the site of trough. The clini- cal effects, lasting time and side effects were observed. Results The tear trough deformities in all cases were improved immediately. The improvement percentages were 95.5% , 84.7% and 52.3% at 1,3 and 6 months, respectively. After follow-up, the effect of the improvement were 43.7% during 6-12 months and 15.8% dur- ing 12-18 months. Non severe complications such as allergic reaction, infection, granulomas and embolism were found after injection. Conclusion HA is a safe and effective dermal filler for the treatment of tear trough deformity.