阿奇霉素治疗小儿支原体肺炎的临床研究

Clinical study of azithromycin in the treatment of mycoplasma pneumonia in children

目的研究阿奇霉素对小儿支原体肺炎的临床治疗效果。方法采用病例对照研究的方法,比较两组在治疗小儿支原体肺炎过程中主要症状消失或缓解的时间、住院时间和治疗效果。结果治疗组咳嗽停止的时间为(6.41±1.52)d,明显少于对照组的(7.72±1.62)d,两组比较差异有统计学意义(P<0.05)。治疗组的住院时间为(6.62±1.34)d,明显少于对照组的(8.41±1.65)d,两组比较差异有统计学意义(P<0.05)。治疗组总有效率为94.44%,明显高于对照组的76.32%,两组比较差异有统计学意义(P<0.05)。对照组不良反应发生率为26.32%,治疗组不良反应发生率为8.33%,二者比较差异有统计学意义(P<0.05)。结论阿奇霉素对治疗小儿支原体肺炎具有较好疗效。

Objective To investigate the clinical treatment of azithromycin for mycoplasma pneumonia in children.Methods The method of case-control study was used and two groups were compared in the treatment of mycoplasma pneumonia in the course of the main symptoms disappeared or mitigate time,duration of hospitalization and treatment.Results The time of stopping cough in treatment group was （6.41±1.52） days,which was significantly less than the （7.72±1.62） days of control group （P 0.05）.The duration of hospitalization was （6.62±1.34） days in treatment group which was significantly less than the control group of （8.41±1.65） days （P 0.05）.The total effective rate was 94.44% in treatment group,which was significantly better than 76.32% in the control group （P 0.05）.The incidence of adverse reactions in control group was 26.32% and it was only 8.33% in treatment group,which was significantly different between them（P0.05）.Conclusion Azithromycin has a better effect in the treatment of mycoplasma pneumonia in children.