摘要
哮喘是儿童时期最常见的慢性呼吸道疾病,目前认为哮喘是一种持续性气道炎症性疾病,可能是系统性炎症的局部表现。观察性研究提示,体内的不同激素都可能影响哮喘的炎症状态,并决定哮喘的进程。同时认识到肥胖在代谢综合征的发生中起了一个主要的作用,并且发现肥胖是如2型糖尿病等慢性炎症性疾病的一个重要危险因素。
出处
《中华儿科杂志》
CAS
CSCD
北大核心
2012年第10期750-752,共3页
Chinese Journal of Pediatrics
基金
上海市科委重大科技攻关项目(10DZ1951100)
参考文献27
-
1Global strategy for asthma management and prevention, (updated 2011): Global Initiative for Asthma (GINA) 2011. [ R/OLd. [2012-07-241 http://www, ginasthma, org/uploads/users/files/ GINA_Report201 l_May4, pdf.
-
2Selassie M, Sirtha AC. The epidemiology and aetiology of obesity : a global challenge. Best Pract Res Clin Anaesthesiol, 2011,25 : 1- 9.
-
3Tesse R, Schieck M, Kabesch M. Asthma and endocrine disorders: shared mechanisms and genetic pleiotropy. Mol Cell Endocrinol, 2011, 333 : 103-111.
-
4Guerra S, Wright AL, Morgan WJ, et al. Persistence of asthma symptoms during adolescence: role of obesity and age at the onset of puberty. Am J Respir Crit Care Med, 2004, 170:78-85.
-
5Beuther DA. Recent insight into obesity and asthma. Curr Opin Pulm Med, 2010,16:64-70.
-
6Black MH, Smith N, Porter AH, et al. Higher prevalence of obesity among children with asthma. Obesity (Silver Spring ), 2012, 20 : 10gl-1047.
-
7Cottrell L, Neal WA, Ice C, et al. Metabolic abnormalities in children with asthma. Am J Respir Crit Care Med, 2011, 183: 441-448.
-
8HuangSL, Shiao G, Chou P. Association between body mass index and allergy in teenage girls in Taiwan. Clin Exp Allergy, 1999, 29:323-329.
-
9Okabe Y, Adachi Y, hazawa T, et al. Association between obesity and asthma in Japanese preschool children. Pediatr Allergy Immunol, 2012,23:550-555.
-
10Magnnsson JO, Kull I, Mai XM, et al. Early childhood overweigh1 and asthma and allergic sensitization at 8 years of age. Pediatrics 2012, 129:70-76.
同被引文献51
-
1Wong GW, Kwon N, Hong JG, et al. Pediatric asthma control in Asia : phase 2 of the Asthma Insights and Reality in Asia-Pacific ( AIRIAP 2 ) survey [ Jl- Allergy,2013,68 (4) :524-530.
-
2Ferrante G, Malizia V, Antona R, et al. The value of FeNO measure- ment in childhood asthma:uncertainties and perspectives [ J ]. Mul- tidiscip Respir Med, 2013,8 ( 1 ) :50.
-
3Rapino D, Attanasi M, Consilvio NP, et al. Evaluation of association between airway hyperresponsiveuess, asthma control test, and asthma therapy assessment questionnaire in asthmatic children [ J ]. blultidis- eip Respir Med,2013,8( 1 ) :48.
-
4Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention [ J/ON ]. Updated 2012. http://www, ginasthma. org/local/uploads/files/GINA Report_Marchl3. pdf (Accessed 20 September 2013 ).
-
5Kelly HW, Sternberg AL, Lescher R, et al, Effect of inhaled glucocor- ticoids in childhood on adult height[ J]. N Engl J Med,2012,367 (10) :904-912.
-
6Zhang L, Axelsson I, Chung M, et al. Dose response of inhaled eorti- eosteroids in children with persistent asthma: A systematic review [ J ]. Pediatrics,2011,127 ( 1 ) : 129-138.
-
7Papadopoulos NG,Arakawa H, Carlsen KH,et al. International consen- sus on (ICON) pediatric asthma[J]. Allergy,2012,67(8):976-997.
-
8Krishnan JA, Bender BG, Wamboldt FS, et al. Adherence to inhaled cortieosteroids:an ancillary study of the childhood asthma manage- ment program clinical trial [ J ]. J Allergy Clin Immunol, 2012,129 (1):112-118.
-
9McNicholl DM, Stevenson M, McGarvey LP, et al. The utility of frac- tional exhaled nitric oxide suppression in the identification of nonad- herence in difficult asthma[ J]. Am J Respir Crit Care Med,2012, 186(11) :1102-1108.
-
10McLaughlin T, Leibman C, Patel P, et al. Risk of recurrent emergency department visits or hospitalizations in children with asthma receiving nebulized budesonide inhalation suspension compared with other asthma medications [ J ]. Curt Med Res Opin, 2007,23 ( 6 ) : 1319 - 1328.
引证文献5
-
1洪建国.儿童哮喘控制药物的合理选择[J].实用医院临床杂志,2013,10(6):4-8. 被引量:4
-
2陈波,冯帅,尹晓文.肥胖对哮喘预测指数阳性喘息婴幼儿治疗效果的影响[J].中国当代儿科杂志,2016,18(10):991-994. 被引量:4
-
3冯艳华.哮喘儿童家庭管理的研究现状[J].全科护理,2017,15(10):1185-1188. 被引量:4
-
4田锋,戴银芳.肥胖症合并哮喘急性期儿童血液指标和炎性因子变化[J].热带医学杂志,2017,17(9):1181-1183. 被引量:2
-
5林榅银,戴燕波.不同体质量哮喘儿童生活质量和健康行为的调查研究[J].中国妇幼保健,2021,36(22):5269-5271. 被引量:4
二级引证文献18
-
1崔恒.茶碱缓释片联合吸入布地奈德气雾剂与酮替芬治疗儿童哮喘临床疗效观察[J].医学信息(医学与计算机应用),2014,0(7):346-347. 被引量:1
-
2娄春艳,李敏,李兰,蒋虹,姚斌.成都中心城区及周边农村儿童哮喘治疗情况的对比分析[J].实用医院临床杂志,2014,11(5):153-155.
-
3蒋虹,李敏,李兰.以胸闷为主要表现的儿童支气管哮喘16例临床分析[J].实用医院临床杂志,2014,11(5):207-208. 被引量:8
-
4王爱华,陈文君,徐建亚,赵霞.固本防哮饮含药血清对IL-4刺激的人胚肺成纤维细胞中ADAM33、ETS1表达的影响[J].中华中医药杂志,2017,32(4):1742-1746. 被引量:3
-
5孙洪华.健脾益肺口服液对小儿哮喘缓解期气道炎症和肺功能的影响[J].中国中西医结合儿科学,2016,8(6):578-580. 被引量:3
-
6蔡兴俊,黄奕江,郑亚妹.胆木提取物对哮喘小鼠肺泡灌洗液中炎性细胞及细胞因子的影响[J].中国热带医学,2018,18(5):427-429. 被引量:5
-
7蒋卡丽,易绘,肖奕青.肥胖对哮喘预测指数阳性患儿预后转归的影响分析[J].中国医学创新,2018,15(20):102-105. 被引量:1
-
8田冰,刘璟.紫菜多糖对哮喘大鼠模型树突状细胞CD80、CD86表型表达的影响[J].热带医学杂志,2018,18(7):873-876. 被引量:3
-
9林依青.英国学校护士的哮喘实践对我国儿童哮喘护理的启示[J].护士进修杂志,2018,33(19):1820-1823. 被引量:4
-
10上官静,王爱敏,梁萍萍,张玉钰,张宇辰.哮喘儿童家庭反应对气道炎症及哮喘控制水平的影响[J].解放军护理杂志,2018,35(16):27-31. 被引量:11
-
1吴亮亮,颜春松.慢性阻塞性肺疾病并发症研究进展[J].中国老年学杂志,2016,36(16):4127-4130. 被引量:28
-
2陈欢乐,李素蘋.英夫利西单抗治疗类风湿性关节炎的护理[J].护理与康复,2010,9(4):358-359. 被引量:4
-
3刘宏琴,蒋田华.浅谈哮喘病人的健康教育[J].基层医学论坛,2004,8(2):174-175.
-
4丁珠云.支气管哮喘病人的家庭护理[J].临床肺科杂志,2005,10(3):345-345. 被引量:2
-
5陈红,邓佳,冯玉麟.慢性阻塞性肺疾病相关性贫血[J].中国呼吸与危重监护杂志,2009,8(6):606-608. 被引量:10
-
6魏云,李崇进,陈勇,刘前程,王萍.大面积烧伤患者血尿酸降低的机理[J].国际检验医学杂志,2006,27(9):856-857.
-
7恶性肿瘤之化疗护理原则[J].健康之路,2006(8):27-29.
-
8曹长云,卢素英,袁瑞雪.人工全髋关节置换手术前后的护理[J].井冈山医专学报,2000,7(3):82-83. 被引量:2
-
9郭安臣,左萍萍.一种新的由感染引发的系统性炎症的标记物-前降钙素[J].中华医院感染学杂志,2003,13(10):993-994. 被引量:34
-
10杨英,龚光凤.机械通气治疗重症哮喘的护理体会[J].护士进修杂志,2008,23(8):703-704. 被引量:2