肺楔形切除+纵隔淋巴结采样治疗在早期肺癌患者中的价值

Value of VATS Wedge Resection and Mediastinal Lymph Node Sampling in Early Peripheral Lung Cancer

目的研究肺楔形切除+纵隔淋巴结采样治疗在早期肺癌患者中的临床价值。方法选取2008年1月-2010年1月进行胸腔镜肺楔形切除+纵隔淋巴结采样治疗的60例早期肺癌患者为观察组,同时选取同期行常规开胸肺叶切除术的60例临床早期肺癌患者为对照组,比较两组的临床治疗效果。结果术中出血量及术中后引流时间观察组均明显低于对照组,差异有统计学意义(P<0.05),而手术时间观察组明显高于对照组,差异有统计学意义(P<0.05),术后3年随访发现两组患者局部复发、远处转移、存活率等差异均无统计学意义(P>0.05)。结论胸腔镜下肺楔形切除+纵隔淋巴结采样治疗早期肺癌,临床疗效明显,并且手术创伤较小,值得临床推广应用。

Objective To study the value of video-assisted thoracoscopic surgery （VATS） wedge resection and mediastinal lymph node sampling in early peripheral lung cancer. Methods Totally 60 patients with early stage lung cancer undergoing vide- o-assisted-VATS wedge resection and mediastinal lymph node sampling in our hospital from January 2008 to January 2010 was se- lected as observation group, while 60 cases of early stage lung cancer patients undergoing conventional thoracotomy combined with lobectomy were selected as control group. The clinical therapeutic effect was compared between the two groups. Results The a- mount of intra-operative bleeding and postoperative drainage time of the observation group were significantly lower than these of the control group ,the difference was statistically significant（ P 〈 0.05 ） ;the operation time of observation group was significantly higher than that in the control group, the difference was statistically significant （ P 〈 0.05 ） ; A 3-year follow-up showed that the lo- calized recurrence, distant metastasis, survival rate of both groups had no significant difference （ P 〉 0.05 ）. Conclusion The clinical curative effect of thoraeoscopic pulmonary wedge resection and mediastinal lymph node sampling in treatment of early lung cancer is obvious ,and the operation wound is smaller,it is worthy of clinical application.