胃黏膜相关淋巴组织淋巴瘤(附9例临床分析)

Gastric mucosa-associated lymphoid tissue lymphoma:A clinical analysis of 9 cases

目的探讨胃黏膜相关淋巴组织淋巴瘤的临床特征、诊断、治疗及预后。方法对经临床及病理确诊,且符合Dowson及Isaacson的诊断标准的9例胃黏膜相关淋巴组织淋巴瘤进行回顾性研究。结果临床表现以上腹部不适、腹部包块、反复黑便为主。胃镜下呈现单发及多发息肉样结节状隆起,表面粘膜有糜烂或浅表溃疡。术前病理诊断率低,误诊率44.4%。结论胃黏膜相关淋巴组织淋巴瘤临床及内镜的诊断准确率较低;部分患者诊断的确立需要依靠外科病理。

Objective To investigate clinical features,diagnosis,therapy and prognosis of gastric mucosa-associated lymphoid tissue（MALT）lymphoma.Methods Retrospective study was conducted on 9 cases of patients with gastric MALT lymphoma who had been positively diagnosed pathologically as well as clinically.All cases met both Dowson＇s and Isaacson＇s criteria.Results Upper abdominal discomfort,abdominal mass,recurrent melena were major clinical manifestations.Endoscopy examination presented single or multiple polypoids,nodulous elevation with erosion or ulceration on mucosasur.Diagnosis of some cases were missed due to low accuracy of biopsy before operation.The inaccuracy rate was 44.4%.Conclusion Correct diagnosis of gastric MALT lymphoma by clinical investigation and endoscopy is relatively lower.Accurate diagnosis in some cases should be based on surgical pathology.