广州市售中药材中各形态铬的含量分析及其健康风险评价

Determination of Chromium Content in Chinese Herbal Medicines from Guangzhou and its Health Risk Assessment

建立广州市售10种中药材中六价铬、三价铬和总铬含量的浊点萃取-原子吸收检测方法,并对其含量水平和健康风险进行初步评价。结果显示,方法的线性、重现性、仪器精密度和回收率均符合定量分析要求。除葛根外,其他药材中总铬含量均超出国家的限量标准;如果以六价铬含量为标准,则只有柴胡、麻黄根和芦根超出限量标准。从健康风险指数来看,以每天服用一次计算,芦根中的总铬对人体健康存在一定风险,其它药材中中的铬对人体的健康风险很小。

Cloud point extraction （CPE）- atomic absorption spectrometry（AAS） method for determination of trivalent chromium, hexavalent chromium and total chromium in ten kinds of Chinese herbal medicines from Guangzhou was developed, and its health risk assessment was evaluated. With this method, good Linearity, reproducibility precision, and recovery were obtained. The results showed that otal chromium in Chinese herbal medicines were all much higher than national standard, except for Radix pueradiae. And only RADIX BUPLEURIi, RADIX EPHEDRAE and LIGNUM SAPPAN would to exceed the national standard, if choose the concentrations of hexavalent chromium as the standard. The health risk index showed that the concentration of total chromium in LIGNUM SAPPAN will possibly produce health risk of adult person. The health risk possibilities of other Chinese herbal medicines were not significant..