氟哌噻吨美利曲辛片联合头痛宁胶囊治疗偏头痛80例

Flupentixol Melitracen Tablet Combined with Headache Relief Capsule in the Treatment of 80 Migraine Cases

目的观察氟哌噻吨美利曲辛片联合头痛宁治疗偏头痛患者的疗效。方法将80例偏头痛患者随机均分为两组,治疗组给予氟哌噻吨美利曲辛片和头痛宁口服,对照组给予头痛宁,均以4周为1个疗程,根据治疗前后头痛发作次数、持续时间及头痛严重程度的变化进行疗效评定,并用汉密尔顿抑郁量表(HAMD)进行评分。结果两种治疗方法均可显著减少偏头痛发作次数,缩短头痛发作时间,减轻头痛程度(P<0.05);治疗组还可明显减轻患者的抑郁焦虑症状,治疗后2、4周HAMD评分的改善优于对照组,差异有统计学意义(P<0.01);治疗组头痛持续时间的缩短也优于对照组,差异有统计学意义(P<0.05)。结论氟哌噻吨美利曲辛片联合头痛宁治疗偏头痛有较好的疗效。

Objective To observe effect of flupenixol melitracen tablet（Deanxit tablet）combined with headache relief capsule treating migraine patients.Methods 80 cases of migraine were randomly divided into two groups,the treatment group was given flupenixol melitracen and headache relief capsule orally,the control group was given headache relief capsule,4 weeks as 1 course,the headache changes were assessed according to the frequency,duration and severity of the headache before and after the headache treatment,and the Hamilton Depression Rating Scale（HAMD）was used to score.Results The two treatment methods can significantly reduce the number of attacks of migraine headache,shorten the duration and reduce headache severity（P〈0.05）;in the treatment group symptoms of depression and anxiety was also obviously relieved,HAMD score at the second and the fourth week after the treatment was better than the control group,with statistically significant difference（P〈0.01）;the headache duration of the treatment group was also shorter than the control group,the difference was statistically significant（P〈0.05）.Conclusion Flupenixol melitracen tablet combined with headache relief capsule as treatment for migraine has a good effect.