综合干预对慢性阻塞性肺疾病稳定期的作用

Effect of comprehensive intervention on COPD patients in stable phase

目的研究综合干预措施对慢性阻塞性肺疾病稳定期的作用。方法 COPD稳定期患者180名,随机分为三组,每组60名。分别于治疗前及治疗6个月记录肺功能、6分钟步行距离(6MWD)、生活质量评分、运动时最低氧饱和度、体重指数、肺动脉平均压。结果综合治疗组6MWD、生活质量评分、运动时最低氧饱和度、肺动脉平均压较中药治疗组及对照组有明显改善(P<0.05),具有统计学差异。而肺功能、体重指数的变化组间无统计学差异(P>0.05)。结论综合干预措施对COPD稳定期患者有积极作用。

Objective To explore the effect of comprehensive intervention on patients with COPD （ chronic obstructive pulmonm＇y disease） in stable phase. Methods 180 COPD patients in stable phase were randomly divided into 3 groups evenly, and the following indexes were recorded and analyzed 6 months before and after the treatment： data of respiratory function, 6 minutes＇ walk distance （6MWD） , quality of life, lowest movement oxygen saturation, baric index and mean pulmonary artery pressure （MPA）. Results There were significant differences in the improvement of 6 minutes＇walk distance （6MWD）, score of living quality, lowest movement oxygen saturation and MPA among the synthetical treatment group, the Chinese traditional medicine treatment group and the control group （ P 〈 0. 05 ）, but there was no significant difference in the improvement of respiratory function and barie index among the three groups （ P 〉 0. 05 ）. Conclusion Comprehensive intervention has a positive effect for the patients with COPD.