甲状腺素与慢性阻塞性肺疾病患者病情与预后关系

The relationship between thyroxine and COPD patients′ conditions and prognostic

目的根据血清甲状腺激素的变化来评估慢性阻塞性肺病患者的病情与预后。方法对90例健康者(对照组)和125例COPD患者(缓解期、急性加重期无呼衰、急性加重期伴呼衰)进行TT3、FT3、TT4、FT4和TSH水平的检测并对数据进行分析。结果 COPD缓解期甲状腺激素水平与对照组比较,差异无显著性;AECOPD甲状腺激素水平与对照组及COPD缓解期组比较均降低,有显著性差异,其中呼衰组下降最低。结论甲状腺素水平的变化与COPD病情严重程度及预后相关,血清中甲状腺素水平可用于COPD的病情与预后的评估。

Objective To assess the COPD patients＇ conditions and prognostic based on the serum thyroid hormone levels change. Methods The data of 90 non-COPD patients as the control group and 125 COPD patients including their remission stage, acute exacerbations stage, acute exacerbations and respiratory failure stage were detected and analyzed at the level of TT3, F33, TY4, FT4 and TSH. R^ults There was no significant difference between the COPD patients （ stable stage） and the control group. The thyroid hormone level of AECOPD patients was lower than the control group and COPD （stable stage） with significant difference, whereas the thyroid hor- mone level of COPD patients （ acute exacerbations and respiratory failure stage） decreased the most. Conclusion As the change of thy- roxine levels in COPD patients is related to the COPD Patients＇ conditions and prognostic, the serum thyroid hormone levels change can be used to assess the COPD Patients＇ conditions and prognostic.