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COPD血清脂联素与炎症标志物相关性研究 被引量:3

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摘要 目的探讨慢性阻塞性肺疾病(COPD)患者血清脂联素(APN)与炎症标志物相关性。方法比较COPD稳定期组(稳定组)、急性加重期组(急重组)与正常人(对照组)在APN、CRP、IL-6、IL-8和TNF-α的差异,分析APN与CRP、IL-6、IL-8和TNF-α的相关性。结果稳定组和急重组APN、CRP、IL-6、IL-8和TNF-α显著高于对照组(P<0.001);急重组APN、CRP、IL-6、IL-8和TNF-α显著高于稳定组(P<0.001)。稳定组和急重组APN均与CRP、IL-6、IL-8和TNF-α正相关(P<0.05)。结论COPD患者APN与CRP、IL-6、IL-8和TNF-α正相关,可作为COPD炎症标志物。
出处 《临床肺科杂志》 2012年第11期2083-2084,共2页 Journal of Clinical Pulmonary Medicine
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