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叶酸及维生素B_(12)对2型糖尿病患者血浆Hcy的干预作用 被引量：5

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摘要 目的:观察叶酸及维生素B12对2型糖尿病(T2DM)患者血浆同型半胱氨酸(Hcy)水平的影响。方法:选择临床确诊的2型糖尿病伴有高同型半胱氨酸血症患者65例,分为治疗组(33例)与对照组(32例),两组患者均给予二甲双胍降糖治疗,治疗组在此基础上加用叶酸及维生素B12治疗,3周为1疗程。对比分析治疗后两组患者Hcy及血糖水平的变化情况。结果:治疗组患者治疗后血清Hcy水平较治疗前明显下降,比较差异有统计学意义(P<0.05);对照组治疗后Hcy水平较治疗前有所下降,但比较差异无统计学意义(P>0.05)。两组患者治疗后FPG及2hPG水平较治疗前下降,比较差异均有统计学意义(P<0.05)。结论:叶酸及维生素B12对降低2型糖尿病患者血浆Hcy水平有明显作用。
作者 卢岚敏 张丽萍 尹亚华
机构地区 中国人民解放军第
出处 《中国医学创新》 CAS 2012年第28期33-34,共2页 Medical Innovation of China
关键词 叶酸 维生素B12 2型糖尿病 HCY
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献7

二级参考文献28

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共引文献72

同被引文献65

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引证文献5

二级引证文献36

中国医学创新
2012年 第28期

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