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改善胃排空障碍在治疗胃食管反流病中的作用 被引量:10

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摘要 目的:分析埃索美拉唑(耐信)、耐信加多潘立酮或体表胃肠起搏对胃食管反流病(gastroesophageal reflux disease,GERD)合并胃排空障碍的疗效。方法:确诊GERD且经X线胃排空检测证实合并胃排空障碍的60例患者,随机分为3组:A组(耐信口服)、B组(耐信加多潘立酮口服)、C组(耐信加体表胃肠起搏)。分析临床症状评分、胃镜下食管炎、胃排空情况及首次复发时间。结果:①B、C组的临床症状改善及胃镜下食管炎改善无显著差异(P>0.05),且均显著高于A组(P<0.05);②B、C组胃排空改善情况无显著差异(P>0.05);③停药后首次复发时间:C组较B组显著延长(P<0.05),B组较A组显著延长(P<0.05)。结论:合并胃排空障碍的GERD患者,予耐信联合多潘立酮或体表胃肠起搏,症状评分及食管炎的改善优于单用耐信治疗;且耐信联合胃肠起搏者比联合多潘立酮治疗者首次复发时间延迟。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2012年第9期1259-1262,共4页 Journal of Nanjing Medical University(Natural Sciences)
基金 无锡市卫生局指导项目(ZD0808)
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参考文献10

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