鸡矢藤水煎液抗炎与镇痛作用的研究

A study on anti-inflammatory and analgesic effects of the paederiae decoction

目的:观察鸡矢藤的抗炎镇痛作用。方法:采用毛细血管通透性法和耳肿胀法观察鸡矢藤的抗炎作用;采用扭体法观察鸡矢藤的镇痛作用。各组动物连续给药3d后,分别检测小鼠腹腔内依文思兰的渗出量、耳肿胀度、扭体反应次数。结果:鸡矢藤能显著降低醋酸所致小鼠腹腔毛细血管通透性的增高,抑制二甲苯所致小鼠耳廓肿胀,减少醋酸刺激所致的小鼠扭体反应次数。结论:鸡矢藤具有明显抗炎和镇痛作用。

Objective： To observe the anti-inflammatory and pain-easing function of paederiae. Methods： To observe the anti-inflammatory effects of paederiae by the capillary permeability law and ear edema method; and to observe the analgesic effects by Niuti method. After 3 days of continuous administration in each group, to detect the exudation of Yiwen Silan in mice intraperitoneal, the ear swelling and the number of writhing. Results： Paederiae can restrain the growth of the permeability of capillary and the auricle swelling by dimethy-phenanthrene, inhibit xylene-induced ear edema, and reduce the times of body-twist caused by acetic acid. Conclusions： Paederiae has obvious anti-inflammmory and analgesic function.