补肾宁心法调节子宫切除术后卵巢功能的临床研究

Bushen Ningxin law regulation of ovarian function after hysterectomy for clinical research

目的比较绝经前妇女行子宫切除术后表现为阴虚火旺证患者治疗前后血清雌二醇(E2)、促卵泡素(FSH)、促黄体生成素(LH)水平的变化,探讨补肾宁心法调节子宫切除术后卵巢功能的临床疗效。方法选择因子宫良性病变行子宫切除术后表现为阴虚火旺的患者60例,随机分为治疗组、对照组,分别测定术前、术后6个月、12个月E2、LH、FSH水平。结果治疗组与对照组术后6个月及12个月血清LH、FSH水平与术前比较均上升;血清E2均有一定程度的下降。但治疗组FSH,LH上升幅度明显减少,E2下降幅度较少。结论子宫切除后影响下丘脑垂体卵巢轴的功能,使卵巢功能降低,出现一系列烘热出汗,头目眩晕,五心烦热,焦虑急躁等临床症状,补肾宁心法能明显改善子宫切除术后患者阴虚火旺的临床证候,调节卵巢功能。

Objective observe the clinical application of the Bushenningxin method on the adjusting the ovarian function of women,who are deficient of yin and excessive of fire syndrome after hysterectomy.Compare the level of Follicle Stimulating Hormone（FSH）、Luteinizing Hormone（LH）、Estradiol（E2） before and after treatment.Discusses its clinical curative effect of adjusting ovarian functions.Methods Select 60 wemon who had undergone hysterectomy and are performance of the fire for Yin deficiency,and then divided them into two groups,namely,the treatment group of 30,the control group of 30.Record the changes of Follicle Stimulating Hormone（FSH）、Luteinizing Hormone（LH）、Estradiol（E2） before and six and twelve months after hysterectomy.Results The FSH and LH level of two groups raise obviously after hysterectomy（P0.05）,but the FSH and LH level of treatment group raise less than control group.The Estradiol（E2） level of two groups all reduce after hysterectomy（P0.05）,and the Estradiol（E2） level of treatment group reduces slightly.Conclusion The hysterectomy influences wemons＇Hypothalamic-pituitary-ovarian axis function,and makes ovarian function reduced,results in a series of clinical symptoms,such as baking hot perspiration,vertigo,upset,anxiety and impatience.The Bushenningxin method can improve the TCM syndromes obviously.and control ovarian functions.