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结直肠癌患者血清CEA、CA199水平与临床病理因素及预后的关系 被引量:5

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摘要 目的:探讨结直肠癌患者血清CEA、CA199水平与临床病理因素及预后的关系。方法:选取首次入院并行手术治疗的结直肠癌患者55例,术后给予FOLFOX方案巩固化疗4~6周期。术前均进行血清CEA及CA199检测,分析其表达与结直肠癌各临床病理因素以及生存结局的关系。结果:Ⅰ、Ⅱ期患者的血清CEA及CA199阳性率明显低于Ⅲ、Ⅳ期患者,比较差异有统计学意义(P〈0.05);其余不同性别、年龄及肿瘤部位患者的血清CEA及CA199阳性率比较差异均无统计学意义(P〉0.05)。存活组患者血清CEA及CA199的阳性率均明显低于死亡组,比较差异均有统计学意义(P〈0.05)。结论:结直肠癌患者术前血清CEA及CA199阳性表达与肿瘤分期明显相关,并可对术后及术后巩固化疗疗效起到预测作用。
出处 《中国医学创新》 CAS 2012年第29期38-39,共2页 Medical Innovation of China
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