2004—2011年秦皇岛市丙型肝炎流行情况

Prevalence of hepatitis C in Qinhuangdao City from 2004-2011

目的探讨秦皇岛市丙型病毒性肝炎(丙肝)流行规律,为制定预防控制策略提供依据。方法利用国家疾病监测系统中的监测数据,用描述流行病学方法对秦皇岛市2004—2011年的丙肝及相关传染病三间分布资料进行描述和分析。结果 8年中,秦皇岛市和青龙县丙肝发病数呈指数函数增长(R2=0.988 5和R2=0.985 8),二者呈高度正相关,差异有统计学意义(r=1.00,P<0.01)。8年中,年平均发病率秦皇岛市上升9.05倍,青龙县上升46.23倍,2011年秦皇岛市和青龙县发病率分别为22.72/10万和99.85/10万。青龙县丙肝的高发地区主要集中在9个地区,占全县的92.18%。45～75岁为高发年龄。男女性别比为2.17∶1。青龙县乙型肝炎和艾滋病的分布与丙肝不同。结论上世纪末安纳珈注射史仍然是青龙县丙肝流行的主要原因,丙肝流行并未伴随其他血行传播传染病的流行,但是已经构成严重的社会问题,应当引起有关部门重视。

[Objective]To understand the epidemiological laws of hepatitis C in Qinhuangdao City,and provide evidence for developing control measures.[Methods]Descriptive epidemiological analysis was conducted on the data of hepatitis C in population,place and time distribution about Qinhuangdao City from 2004-2011 collected from Disease Surveillance Data Report and Management System.[Results] During 8 years,the cases of hepatitis C had increased exponentially in Qinhuangdao City and QingLong county.Regression coefficients were equal to 0.998 5 and 0.995 8 which were statistical significantly positive correlated,（r=1.00,P0.01）.The average annual incidence had increased 9.05 times in Qinhuangdao city and 46.23 times in Qinglong County,and that was 22.72/100 000 and 99.85/100 000 in 2011.There were 9 areas in Qinglong County with high incidence areas,occupying 92.18% of total incidence.The high risk age group was 45-75 years age group.The ratio of male and female was 2.17∶1.The distribution of hepatitis C was different from that of AIDS and hepatitis B.[Conclusion]The main reason for hepatitis C epidemic is the injection history of Annajia at the end of the last century in Qinglong County,although it does not accompany with other blood transmitted diseases,it has constituted a serious social problem which should attract more attention from relevant department.