摘要
目的:研究东北刺人参挥发油中抗真菌活性成分。方法:按新版中国药典中水蒸气蒸馏法提取东北刺人参挥发油,采用试管内药基法研究其抗真菌活性,利用GC-MS分析其抗真菌活性成分。结果:东北刺人参挥发油抗真菌活性MIC为0.034%~0.063%,MFC为0.070%~0.126%,挥发油中水溶性成分共18个,已鉴定其中12个化合物,占挥发油总量的90.71%,其中萜烯醇类化合物占89.83%,橙花叔醇占38.40%,毕橙茄醇占28.44%。结论:东北刺人参挥发油中水溶性成分抗真菌活性更显强,主要化学成分为橙花叔醇和毕橙茄醇。
Objective: To study the antifungal active constituent of essential oil from Oplopanax elatus. Method : The essential oil of Oplopanax elatus was steam-distilled according to the China Pharmacopoeia to extract. Antifungal activity studies were carried out in vitro and antifungal active constituent were analyzed by GC-MS. Result: Antifungal active MIC of essential oil from Oplopanax elatus ranged from 0. 034%-0. 063% and MFC 0.070%-0. 126%. 18 components were obtained from water-soluble essential oil and 12 components were identified. 89.83% of them were terpenol compounds, nerolidol ( 38.40% ) and T-cadinol ( 28.44% )Conclusion: Antifungal activity of water-soluble essential oil from Oplopanax elatus was strong. The main components were nerolidol and T-cadinol.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第21期136-138,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
吉林省中医药管理局(吉中医0251)