解郁定悸汤治疗中青年妇女心律失常

Clinical Observation of Jieyu Dingji Decoction on Arrbythmia of Yang and Middle-aged Women

目的:观察解郁定悸汤治疗中青年妇女心律失常的临床疗效。方法:选择有室上性早搏、室性早搏等心律失常的中青年妇女60例,随机分成治疗组和对照组各30例,治疗组采用自制方解郁定悸汤+美托洛尔片12.5～50 mg治疗,对照组服用安慰剂+美托洛尔片12.5～50 mg治疗,评价两组的治疗效果、副作用及复发情况。结果:治疗组和对照组治疗后的临床症状及动态心电图表现均较治疗前有显著改善,但治疗组的疗效优于对照组(P<0.05)有效率达93%,且复发少(P<0.05),两组均无明显不良反应。结论:解郁定悸汤治疗中青年妇女心律失常疗效确切,安全性较好,为临床用药提供了一个新选择。

Objective： This clinicat study aims to investigate the effects of Jieyu Dingji decoction on the arrhythmia of young and middle-aged women. Method： Sixty young and middle-aged women with ventricular premature beats or superaventricular premature beats were chosen and randomized into treatment group and control group with thirty people respectively. The treatment group was treated with Jieyu Dingji decoction and metoprolol, and the control group was treated with placebo and metoprolol. The efficacy, side effects and recrudescence of the two groups were then investigated. Result： The symptoms and the ambulatory electrocardiographs of both groups were improved after therapy. However, the efficacy of the treatment group was superior to the control group （P 〈 0.05） , and the recrudescence of the treatment group was less than the control group （P 〈 0.05）. Neither of the groups shows adverse events. Conclusion： Jieyu Dingji decoction is effective and safe to treat young and middle- aged women with arrhythmia. It provides an innovated way for the clinical medication.