淫羊藿、女贞子抗骨质疏松症的应用与机制研究进展

Advances on Studies of Anti-osteoporosis Applications and Mechanisms by Herba Epimedii and Fructus Ligustri Lucidi

对中药淫羊藿、女贞子抗骨质疏松症(OP)的作用机制及临床应用的相关研究进行文献整理和分析。通过中国知网和Pubmed检索工具,以淫羊藿、女贞子、抗骨质疏松为主题词检索近5年的相关文献,筛选整理后对淫羊藿、女贞子的抗OP作用进行介绍。分别概述了淫羊藿、女贞子防治OP的临床应用报道,并对二药抗OP作用机制的相关研究进展进行了分析。淫羊藿、女贞子在防治OP方面具有显著疗效,但开发研究尚处于初级阶段,复方制剂远期疗效尚不明确且未闻淫羊藿、女贞子配伍抗OP作用的相关报道。研究初步证实,二药配伍用于临床防治OP具有广阔的前景。

To study the anti-osteoporosis applications and mechanisms of Herba Epimedii and Fructus Ligustri Lucidi with the collation and analysis of litertures. Herba Epimedii, Fructus Ligustri Lucidi and anti- osteoporosis as the subject headings are used to screen litertures in the last five years by CNKI and Pubmed, and then make an overview of anti- osteoporosis effects of Herba Epimedii and Fructus Ligustri Lucidi. This anticle summarizes the clinical application reports of anti-osteoporosis by Herba Epimedii and Fructus Ligustri Lucidi, and analyzes the progress in the study of the mechanisms of anti-osteoporosis effect of the two herbs. Herba Epimedii and Fructus Ligustri Lucidi has made a significant effect in the prevention and treatment of osteoporosis, but the development of research is in its infancy, long-term efficacy of the compound preparation is inaccurate, and do not find the reports of the two herbs compatibility of anti-osteoporosis. So research on compatibility of the two herbs in the anti-osteoporosis has broad prospects.