开放性下肢长骨骨折与肺血栓栓塞的相关性的研究

Correlatoin Research of Open Lower Limb Long Bone Fracture and the Lung Thrombus Embolism

目的：研究开放性下肢长骨骨折与肺血栓栓塞之间的相关性,提高开放性下肢长骨骨折并发肺血栓栓塞患者的生存率。方法：回顾性分析2008年1月~2009年12月在北京中日友好医院诊断为开放性下肢长骨骨折,并术后下肢静脉彩色多普勒超声检查的240例患者,观察住院期间发生下肢静脉血栓形成、肺血栓栓塞情况,分析年龄、性别、高血压病、糖尿病、血脂情况、吸烟、体重指数与血栓形成的相关性。结果：住院期间99例患者发生下肢静脉血栓形成,其中股骨骨折组48例、胫腓骨骨折组51例,两组无统计学意义（P=0.969）。下肢静脉血栓形成和无下肢静脉血栓形成两组在年龄、女性、糖尿病、血脂代谢异常等方面有统计学意义（P〈0.05）。下肢静脉血栓形成患者中18例发生肺血栓栓塞,其中股骨骨折组8例,胫腓骨骨折组10例,两组差异无统计学意义（P=0.212）。下肢静脉血栓形成患者中有肺血栓栓塞和无肺血栓栓塞两组在年龄、高血压、糖尿病、血脂代谢异常等差异有统计学意义（P〈0.05）。结论：开放性股骨及胫腓骨骨折在下肢静脉血栓栓塞形成例数相似,年龄、女性、糖尿病、血脂代谢异常及体重指数是下肢静脉血栓形成的危险因素,下肢静脉血栓形成患者中年龄、高血压、糖尿病及血脂代谢异常是肺血栓栓塞的危险因素。

Objective：The research open lower limb long bone bone fracture and between the lung thrombus embolism＇s relevance,raises the open lower limb long bone bone fracture concurrent lung thrombus embolism patient＇s survival rate.Methods： Review analysis in January,2008-December,2009 in Beijing Sino-Japanese friendship Hospital diagnosis for open lower limb long bone bone fracture,after and technique,lower limb vein colored Doppler supersonic inspection 240 example patient,observation in hospital period has the lower limb phlebothrombosis,the lung thrombus embolism situation,the relevance which the analysis age,the sex,hypertension sickness,diabetes,the blood fats situation,smoking,the body weight index and the thrombus form.Results： In hospital period 99 example patients have the lower limb phlebothrombosis,thighbone bone fracture group 48 examples,shin fibula bone fracture group 51 examples,two group of non-statistics differences（P=0.969）.The lower limb phlebothrombosis and the non-lower limb phlebothrombosis two groups in aspects and so on age,female,diabetes,blood fats metabolic anomalies have statistics difference（P0.05）.In the lower limb phlebothrombosis patient 18 examples have the lung thrombus embolism,thighbone bone fracture group 8 examples,shin fibula bone fracture group 10 examples,two group of non-statistics differences（P=0.212）.In the lower limb phlebothrombosis patient has the lung thrombus embolism and the non-lung thrombus embolism two groups in the age,hypertension sickness,diabetes,the blood fats metabolic anomalies and so on has statistics difference（P0.05）.Conclusion： The open thighbone and the shin fibula bone fracture is similar in the lower limb vein thrombus embolism shape precedent,the age,feminine,diabetes,the blood fats metabolic anomalies and the body weight index is the lower limb phlebothrombosis hazard factor,in the lower limb phlebothrombosis patient the age,hypertension sickness,diabetes and the blood fats metabolic anomalies is the lung thrombus embolism＇s hazard factor.